The San Francisco 49ers have been unable to escape their injury woes this season. Christian McCaffrey missed significant time with a leg injury and just made his season debut a couple of weeks ago. Their star wide receiver Deebo Samuel has also missed time, and they recently lost their star receiver Brandon Aiyuk for the season. And despite their injury woes, for a while, the 49ers kept finding a way to gut out wins and stay afloat in the NFC West. But they recently hit a rough patch that has been a struggle to overcome as they have lost three of their last five games. But despite being last in their division, the 49ers aren’t dead in the water just yet as the race for the NFC West is tight, and a couple of wins could catapult them to first place.
The Bills are still riding high after knocking off the undefeated Kansas City Chiefs in Week 11. And even though they are sitting in first place in the AFC East they cannot afford to get too relaxed and the playoffs draw nearer. In a stacked AFC the Bills will be trying to secure home-field advantage throughout the playoffs. Not to mention that their division rival, the Miami Dolphins have been surging since Tua Tagaviloa’s return. One key player to watch in this matchup will be the Bills newly-acquired wide receiver Amari Cooper. Cooper played a major role in Buffalo’s win over the Chiefs, notching two timely receptions for 55 yards. Buffalo will be looking for a little more out of Cooper this week, against a stout San Francisco defense.
